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俞芳　副研究员

上海师范大学质体生物学实验室 · 副研究员

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代表性科研项目

  1. 线粒体Ups蛋白转运磷脂的分子机理研究，国家自然科学基金（青年项目），2015-2017，项目负责人。
  2. 叶绿体重要生理过程蛋白质的结构与机理解析，国家科技部青年973项目，2015-2019，项目骨干。

代表性论文及著作

  1. Fang Yu#, Fangyuan He #, Hongyan Yao, Chengyuan Wang, Jianchuan Wang, Jianxu Li, Xiaofeng Qi, Hongwei Xue *, Jianping Ding *, Peng Zhang *. Structural basis of intramitochondrial phosphatidic acid transport mediated by Ups1-Mdm35 complex. EMBO Rep. 2015. 16 (7). 813-23.
  2. Ke Xu #, Minhua Zhang #, Qin Zhao#, Fang Yu#, Hui Guo, Chengyuan Wang, Fangyuan He, Jianping Ding, Peng Zhang. Crystal structure of a folate energy-coupling factor transporter from Lactobacillus brevis.Nature. 2013; 497(7448):268-71.
  3. Todd M. Greco#, Fang Yu #, Guise AJ, Ileana M. Cristea. Nuclear import of histone deacetylase 5 by requisite nuclear localization signal phosphorylation.Mol Cell Proteomics. 2011;10(2):M110.004317. Amanda J. Guise, Rommel A.Mathias, Elizabeth A. Rowland, Fang Yu, Ileana M. Cristea. Probing phosphorylation-dependent protein interactions within functional domains of histone deacetylase 5 (HDAC5).Proteomics.2014; 14(19):2156-66.
  4. Preeti Joshi, Todd M. Greco, Amanda J. Guise, Yang Luo , Fang Yu , Alexey I. Nesvizhskii, Ileana M. Cristea. The functional interactome landscape of the human histone deacetylase family.Mol Syst Biol. 2013;9:672.
  5. Amanda J. Guise, Todd M. Greco, Irene Y. Zhang , Fang Yu, Ileana M. Cristea. Aurora B-dependent regulation of class IIa histone deacetylases by mitotic nuclear localization signal phosphorylation. Mol Cell Proteomics. 2012;11(11):1220-9.
  6. Yang Luo#, Tuo Li#, Fang Yu, Tal Kramer, Ileana M. Cristea. Resolving the composition of protein complexes using a MALDI LTQ Orbitrap. J Am Soc Mass Spectrom.2010; 21(1):34-46.
  7. Ye Yu, Zhi Chen, Weiguang Li, Hui Cao, Enguang Feng, Fang Yu, Hong Liu, Hualiang Jiang, Tianle Xu. A nonproton ligand sensor in the acid-sensing ion channel.Neuron. 2010; 68(1):61-72.
  8. Huaiyu Yang, Ye Yu, Weiguang Li, Fang Yu, Hui Cao, Tianle Xu, Hualiang Jiang. Inherent dynamics of the acid-sensing ion channel 1 correlates with the gating mechanism. PLoS Biology. 2009; 7(7): e1000151.
  9. Xiaobing Zhang, Guangcun Sun, Luying Liu, Fang Yu, Tianle Xu. Alpha2 subunit specificity of cyclothiazide inhibition on glycine receptors.Mol Pharmacol. 2008;73(4):1195-202.
  10. Ziqiang Liu, Yan Zhu, Juan Gao, Fang Yu, Aiwu Dong, Wenhui Shen. Molecular and reverse genetic characterization of NUCLEOSOME ASSEMBLY PROTEIN1 (NAP1) genes unravels their function in transcription and nucleotide excision repair in Arabidopsis thaliana. Plant J. 2009;59(1):27-38.
  11. Aiwu Dong, Ziqiang Liu, Yan Zhu, Fang Yu, Ziyu Li, Kaiming Cao, Wenhui Shen. Interacting proteins and difference in nuclear transport reveal specific functions for the NAP1 family proteins in plants. Plant Physiol. 2005 ;138(3):1446-5.

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